Menu   WellSpan Health

Health Library

Health Library

The Genetics of Lung Cancer

The majority of lung cancer deaths (about 80%) are due to cigarette smoking. A number of diverse genetic abnormalities have been identified in lung cancer cells. Some of these genetic abnormalities may be causal (for example, responsible for initiating the development of cancer), while others may instead indicate the progression of the cancer.

Not everyone who smokes will develop lung cancer. Studies have identified that normal genetic variations — polymorphisms — in the population may make some individuals more likely to develop lung cancer if they smoke than other smokers (without the polymorphism).

Genetic polymorphisms may also be important for nonsmokers, some of whom are still exposed to tobacco smoke at work or in the home. Certain genetic polymorphisms have been found to be associated with a greater risk of lung cancer development, even in a person who has never smoked. This may explain why relatives of people with lung cancer, regardless of whether they smoke or not, have an increased chance of developing lung cancer. Additional studies are needed to better understand these gene-environment interactions.

The Genetics of Lung Cancer - WellSpan Health

Online Medical Reviewer: Foster, Sara, RN, MPH
Online Medical Reviewer: MMI board-certified, academically affiliated clinician
Last Review Date: 2013-11-26T00:00:00
Last Modified Date: 2013-12-19T00:00:00
Posting Date: 2008-11-30T00:00:00
Published Date: 2013-12-19T00:00:00
Last Review Date: 2012-06-07T00:00:00
© 2015 WellSpan Health. All Rights Reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

I would like to:

Are you sure you would like to cancel?

All information will be lost.

Yes No ×

About the provider search

This search will provide you with WellSpan Medical Group and Northern Lancaster County (Ephrata) Medical Group primary care physicians and specialists. If we don’t have a WellSpan Medical Group physician to meet your criteria, the search will expand to include community physicians who partner with WellSpan Medical Group physicians through the WellSpan Provider Network or provide care to patients on the Medical Staffs of WellSpan’s Hospitals.

×

Schedule Your Next Appointment Online with MyWellSpan

Use your MyWellSpan patient portal any time to view available appointments, and pick the date and time that best suits your schedule.

Go to MyWellSpan

New to this practice?

If you don't have a WellSpan primary care provider and would like to schedule a new patient appointment with a provider who is accepting patients, just log into your MyWellSpan account, and go to the Appointment Center section. As you progress through the scheduling process, you will be able to see the offices that are accepting new patients in relation to your zip code. If you are not enrolled in MyWellSpan, go to www.mywellspan.org, call 1-866-638-1842 or speak with a member of the staff at a participating facility to sign up. New patient scheduling not available at all practices/programs.

Already a patient at this practice?

If you already have a relationship with a WellSpan practice, simply log into your account, and go to the Appointment Center section. As you progress through the scheduling process, you will be able to schedule an appointment with any provider or practice that already counts you as a patient. Online scheduling varies by practice/program.

×